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KMID : 1037420070020010028
Journal of Korean Skull Base Society
2007 Volume.2 No. 1 p.28 ~ p.33
Growth Patterns of Brain Stem Glioma
Lee Hong-Jae

Kang Seok-Gu
Lee Tae-Gyu
Lee Kwan-Sung
Jeun Sin-Soo
Lee Sang-Won
Hong Yong-Kil
Park Chun-Kun
Kim Moon-Chan
Abstract
During recent years it has been demonstrated that subgroups of brain stem glioma may be associated with a better prognosis than others. We investigated some correlations between the pathological findings and radiologic (magnetic resonance imaging, computed tomography) imaging appearance of 13 brain stem gliomas, which were able to follow up over 1 year. The growth patterns of brain stem glioma was observed retrospectively. 8 cases were low grade gliomas and 5 cases were high grade gliomas that included three definite diffuse brain stem gliomas in magnetic resonance imagings even though these tumors were not confirmed by pathologist. Superior and dorsal exophytic growth patterns was observed in low grade brain stem glioma and multidirectional growth patterns in high grade brain stem glioma. According to this observation, growth of low grade brain stem glioma has stereotypical growth pattern by barrier and high grade glioma was unhindered by barrier. Growth patterns of brain stem glioma will help to assess the histological grade and establish
the therapeutic plan.
KEYWORD
Growth pattern, Brain stem, Glioma, Therapeutic plan
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